Structural MRI and functional connectivity features predict current clinical status and persistence behavior in prescription opioid users

Examining Brain Networks in Prescription Opioid Users

Prescription opioid dependence has reached epidemic proportions in the U.S. and internationally [1]. Overdose deaths involving prescription opioids have increased significantly since 1999; indeed from 1999 to 2015, more than 183,000 people have died in the U.S. from overdoses related to prescription opioids [2,3]. It is well known that drug addiction is a disease of the brain [4] and thus, ther...

Alterations in brain structure and functional connectivity in prescription opioid-dependent patients.

A dramatic increase in the use and dependence of prescription opioids has occurred within the last 10 years. The consequences of long-term prescription opioid use and dependence on the brain are largely unknown, and any speculation is inferred from heroin and methadone studies. Thus, no data have directly demonstrated the effects of prescription opioid use on brain structure and function in hum...

ultrarapid opioid detoxification: current status in iran and controversies

Clinical applications of PET/MRI: current status and future perspectives.

Fully integrated positron emission tomography (PET)/magnetic resonance imaging (MRI) scanners have been available for a few years. Since then, the number of scanner installations and published studies have been growing. While feasibility of integrated PET/MRI has been demonstrated for many clinical and preclinical imaging applications, now those applications where PET/MRI provides a clear benef...

efl students gender and socioeconomic status: the use of politeness strategies in the first and second languages

within the components of communicative competence, a special emphasis is put on the “rules of politeness,” specifically the politeness strategies (brown and levinson, 1978) that speakers deploy when performing the request speech act. this is because the degree of imposition that making a request places upon one’s interlocutor(s) has been seen to be influenced by several factors among which, as ...